MANCHINEE'L, noun [Latin mancanilla.] A tree of the genus Hippomane, growing in the West Indies to the size of a large oak. It abounds in an acrid, milky juice of a poisonous quality. It bears a fruit of the size of a pippin, which, when eaten, causes inflammation in the mouth and throat, pains in the stomach, etc. The wood is valuable for cabinet work.
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Webster's Dictionary 1828
American Dictionary of the English Language, Noah Webster, 1828.