An‐tag″o‐nism (ăn‐tăg″ō̍‐nĭz'm), n. [Gr. ανταγὤνισμα, fr. ανταγωνἴζεσθαι to struggle against; αντἴ against + αγωνἴζεσθαι to contend or struggle, αγὤν contest: cf. F. antagonisme. See Agony.] Opposition of action; counteraction or contrariety of things or principles.
☞ We speak of antagonism between two things, to or against a thing, and sometimes with a thing.