Bru‐no″ni‐an (�), a. Pertaining to, or invented by, Brown; — a term applied to a system of medicine promulgated in the 18th century by John Brown, of Scotland, the fundamental doctrine of which was, that life is a state of excitation produced by the normal action of external agents upon the body, and that disease consists in excess or deficiency of excitation.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.