Dec′i‐mo‐sex″to (?), n. [Prop., in sixteenth; fr. L. decimus tenth + sextus sixth.] A book consisting of sheets, each of which is folded into sixteen leaves; hence, indicating, more or less definitely, a size of book; — usually written 16mo or 16°.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.