Dis′in‐ure″ (?), v. t. [imp. & p. p.Disinured (?); p. pr. & vb. n.Disinuring.] [Pref. dis- + inure.] To render unaccustomed or unfamiliar.
We are hindered and disinured... towards the true knowledge. Milton.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.