Fag, v. t. 1. To tire by labor; to exhaust; as, he was almost fagged out.
2. Anything that fatigues.
It is such a fag, I came back tired to death. Miss Austen.
Brain fag. (Med.) See Cerebropathy.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.