Lo″co, v. t. [imp. & p. p.Locoed (?); p. pr. & vb. n.Locoing.] To poison with loco; to affect with the loco disease; hence (Colloq.), to render insane or mad. “The locoed novelist.” W. D. Howells.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.