Ru′be‐fa″cient (?), a. [L. rubefaciens, p. pr. of rubefacere to make red; rubere to be red + facere to make.] Making red. — n.(Med.) An external application which produces redness of the skin.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.