Sex′to‐dec″imo, n.; pl.Sextodecimos (�). A book composed of sheets each of which is folded into sixteen leaves; hence, indicating, more or less definitely, a size of a book; — usually written 16mo, or 16°.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.