{ ‖Or′thop‐nœ″a (?), Or‐thop″ny (?), } n. [L. orthopnoea, Gr. �; ορθὄσstraight, right + πνει̑ν to breathe: cf. F. orthopnée.] (Med.) Specifically, a morbid condition in which respiration can be performed only in an erect posture; by extension, any difficulty of breathing.
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Webster's Dictionary 1913
Webster's Revised Unabridged Dictionary, C. & G. Merriam Co., 1913.